Established in 1902 as a day and boarding school for girls from Kindergarten to Year 12, Annesley was first known as Methodist Ladies College and consisted of 19 students.
The College was originally located at Malvern before relocating in 1904 to it’s current home adjacent Greenhill Road at Rose Terrace, Wayville. It was not until 1977 that the College was re-named Annesley College following the amalgamation of the Methodist, Presbyterian and Congregational Churches.